前列地尔注射液治疗后循环缺血性眩晕的临床疗效观察

目的:观察前列地尔注射液对后循环缺血性眩晕的治疗效果。方法:选择后循环缺血性眩晕患者60例,随机分为两组,治疗组30例,对照组30例。治疗组给予前列地尔注射液治疗,对照组给予长春西汀针治疗,10 d后评估疗效。结果:治疗组痊愈10例,显效12例,有效6例,无效2例,总有效率93.3%。对照组痊愈4例,显效6例,有效12例,无效8例,总有效率73.3%。两组总有效率差异有统计学意义(P<0.05)。治疗组平均起效时间(3.5±1.4)d,对照组为(4.7±1.9)d,差异有统计学意义(P<0.05)。结论:前列地尔注射液治疗后循环缺血性眩晕起效快疗效好,且使用安全,值得临床推广应用。

Clinical observation of treatment with Alprostadil injection on posterior circulation ischemic vertigo

Objective To investigate and assess the therapeutic effect of treatment with Alprostadil injection on posterior circulation ischemic vertigo. Method 60 Patients who suffered from posterior circulation ischemic vertigo were randomly divided into two groups： treat- ment group（30 cases） and control group（30 cases）. The treatment group was treated with Alprostadil injection and the control group was treated with Vinpocetin injection, the efficacy was observed after ten days treatment. Results 10 cases were cured, 12 markedly effective ,6 effective and 2 ineffective in the treatment group,and the corresponding figures were 4,6,12 and 8 in the control group,total effective rates in treatment group and control group were 93. 3% and 73.3%, respectively, showing significant difference between two groups （P 〈 0. 05 ） The mean time of initiation of effect in treatment group was （ 3.5 ± 1.4） d and that of control group was （4. 7 ± 1.9） d, comparison of the two groups ,the difference was statistically significant （P 〈0. 05 ）. Conclusion The effect of Alprostadil injection in the treatment of posteri- or circulation ischemic vertigo has the benefits of reacting fast and showing better effect. It is very safe and is worth popularizing in clinical application.