| 石菖蒲冰片对神经细胞缺氧性损伤的保护作用 |
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| 引用本文： | 蒋红兰,匡忠生,李翎,林双峰,魏刚,谢宇晖,方永奇.石菖蒲冰片对神经细胞缺氧性损伤的保护作用[J].广州中医药大学学报,2003,20(1):63-65. |
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| 作者姓名： | 蒋红兰 匡忠生 李翎 林双峰 魏刚 谢宇晖 方永奇 |
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| 作者单位： | 广州中医药大学第一附属医院实验中心,广州,510405 |
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| 摘 要： | 目的 探讨石菖蒲，冰片对缺氧损伤神经细胞的保护作用。方法 在缺氧培养条件下造成大鼠神经细胞损伤，测定空白对照组，模型对照组，石菖蒲挥发油组，冰片组，冰片＋石菖蒲挥发油（低，中，高配比）组神经元细胞数，神经细胞支配面积。结果 石菖蒲挥发油，冰片，冰片＋挥发油（低，中，高配比）给药组神经细胞支配面积和神经元细胞数高于空白对照组和模型对照组。结论 石菖蒲，冰片对缺氧诱导的大鼠神经细胞损伤具有保护作用。
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| 关 键 词： | 脑损伤 中药疗法 神经元 药物作用 石菖蒲 冰片 药理学 |
| 文章编号： | 1007-3213(2003)01-0063-03 |
| 修稿时间： | 2002年8月22日 |
Protective Effect of Borneol and Volatile Oil of Rhizoma Acori Tatarinowii on Anoxic Damage of Nerve Cells |
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| JIANG Honglan,KUANG Zhongsheng,LI Ling,LIN Shuangfeng,WEI Gang,XIE Yuhui,FANG Yongqi.Protective Effect of Borneol and Volatile Oil of Rhizoma Acori Tatarinowii on Anoxic Damage of Nerve Cells[J].Journal of Guangzhou University of Traditional Chinese Medicine,2003,20(1):63-65. |
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| Authors: | JIANG Honglan KUANG Zhongsheng LI Ling LIN Shuangfeng WEI Gang XIE Yuhui FANG Yongqi |
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| Abstract: | Objective] To explore the protective effect of Borneol and volatile oil of Rhizoma Acori Tatarinowii (RAT) on anoxic damage of nerve cells (NC). Methods] NC damage in rats were induced by anoxic culture solution. The number of NC and the domination area of NC in normal control group (Group A), model control group (Group B) , RAT volatile oil group (Group C), borneol group (Group D), borneol (20 g/L) and RAT volatile oil (7.3 g/L, 11 g/L and 14.6 g/L) groups (Group E, Group F and Group G) were measured. Results] The number of NC and the domination area of NC in Group C, Group D, Group E, Group F and Group G were larger than those in Group A and Group B. Conclusion] Borneol and volatile oil of RAT exert a protective effect on anoxic damage of NC. |
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| Keywords: | CEREBRAL DAMAGE/TCD therapy NEURONS/drug effects ACORUS TATARINOWII /phannacology BORNEOLUM SYNTHETICUM/phaimacology |
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