First characterization of fluoroquinolone resistance in Streptococcus suis |
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| Authors: | Escudero Jose Antonio San Millan Alvaro Catalan Ana de la Campa Adela G Rivero Estefania Lopez Gema Dominguez Lucas Moreno Miguel Angel Gonzalez-Zorn Bruno |
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| Affiliation: | Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, 28040 Madrid, Spain. |
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| Abstract: | We have identified and sequenced the genes encoding the quinolone-resistance determining region (QRDR) of ParC and GyrA in fluoroquinolone-susceptible and -resistant Streptococcus suis clinical isolates. Resistance is the consequence of single point mutations in the QRDRs of ParC and GyrA and is not due to clonal spread of resistant strains or horizontal gene transfer with other bacteria. |
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