燕麦麸皮的黄酮类成分(英文)

目的:研究燕麦麸皮的黄酮类化学成分。方法:用95%乙醇回流提取,采用大孔树脂、硅胶、Sephadex LH-20、ODS柱色谱和高效液相色谱制备等方法分离纯化,根据理化性质和光谱数据鉴定化合物的结构。结果:从燕麦麸皮分离得到15个黄酮类化合物,依次为山柰酚3-O-(2",3"-O-二对羟基桂皮酰基)-α-L-鼠李吡喃糖苷(1),山柰酚3-O-(3"-O-对羟基桂皮酰基)-α-L-鼠李吡喃糖苷(2),山柰酚3-O-(2’’-O-对羟基桂皮酰基)-β-D-吡喃葡萄糖苷(3),山柰酚3-O-β-D-吡喃葡萄糖苷(4),山柰酚7-O-α-L-吡喃鼠李糖苷(5),蒙花苷(6),田蓟苷(7),杨梅树皮苷(8),槲皮苷(9),山柰酚3-O-芸香糖苷(10),芦丁(11),小麦黄素7-O-β-D-吡喃葡萄糖苷(12),小麦黄素(13),山柰酚(14),木犀草素(15)。结论:化合物1～9首次从该植物中分离得到。

Flavonoids from the bran of Avena sativa

AIM: To investigate the chemical constituents from the bran of Avena sativa. METHODS: Compounds were isolated and purified by various column chromatographic techniques using macroporous resin, silica gel, Sephadex LH-20, ODS, and prepara-tive reversed-phase HPLC. Their structures were elucidated by physicochemical properties and spectroscopic data. RESULTS: Fifteen chemical constituents were isolated and identified as kaempferol 3-O-(2", 3"-di-E-p-coumaroyl)-α-L-rhamnopyranoside (1), kaempferol 3-O-(3"-E-p-coumaroyl)-α-L-rhamnopyranoside (2), kaempferol 3-O-(2"-O-E-p-coumaroyl)-β-D-glucopyranoside (3), kaempferol 3-O-β-D-glucopyranoside (4), kaempferol 7-O-α-L-rhamnopyranoside (5), linarin (6), tilianin (7), myricitrin (8), quercitrin (9), kaempferol 3-O-rutinoside (10), rutin (11), tricin 7-O-β-D-glucopyranoside (12), tricin (13), kaempferol (14), and luteolin (15). CONCLUSION: Compounds 1-9 were isolated from Avena sativa Linn. for the first time.