| 腰骨藤的植物化学和药理学研究进展(英文) |
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| 作者姓名： | Narendra Kumar Singh V. P. Singh |
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| 作者单位： | Department of Medicinal Chemistry, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, India |
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| 基金项目： | Acknowledgements Authors are thankful to Mr. Ashok Gupta, Department of Pharmacology, IMS, BHU, for providing literature data for this review. |
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| 摘 要： | Ichnocarpus frutescens R. Br. (Apocynaceae), is a woody climbing shrub, found almost in all parts of India. In India, tribes used this plant as a substitute of Indian Sarsaparilla (Hemidesmus indicus) for the treatment of atrophy, convulsions, cough, delirium, dysentery, measles, splenomegaly, tuberculosis, tumor, diabetes as a lactogogue, antipyretic, demulcent, diaphoretic and in skin diseases. Phytochemical investigations indicate that 28 compounds reported from the plant belong to various chemical category viz. phytosterol, triterpenes, flavonoids and various other phenolic compounds. Pharmacological activities of different parts of the plant reported include antiurolithiatic, hepatoprotective, antioxidant, analgesic, antipyretic, anti-inflammatory, antidiabetic, antihyperlipi-demic and antitumor activity. In the present review the literature data on the phytochemical and biological investigations on the I. frutescens are summarized up to March 2011.
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| 关 键 词： | Ichnocarpus frutescens Antitumor Anti-inflammatory Hepatoprotective |
Phytochemistry and pharmacology of Ichnocarpus frutescens |
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| Narendra Kumar Singh,V. P. Singh.Phytochemistry and pharmacology of Ichnocarpus frutescens[J].Chinese JOurnal of Natural Medicines,2012(4):241-246. |
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| Authors: | Narendra Kumar Singh V R Singh |
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| Institution: | Department of Medicinal Chemistry, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005,India |
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| Abstract: | Ichnocarpus frutescens R. Br. (Apocynaceae), is a woody climbing shrub, found almost in all parts of India. In India, tribes used this plant as a substitute of Indian Sarsaparilla (Hemidesmus indicus) for the treatment of atrophy, convulsions, cough, delirium, dysentery, measles, splenomegaly, tuberculosis, tumor, diabetes as a lactogogue, antipyretic, demulcent, diaphoretic and in skin diseases. Phytochemical investigations indicate that 28 compounds reported from the plant belong to various chemical category viz. phytosterol, triterpenes, flavonoids and various other phenolic compounds. Pharmacological activities of different parts of the plant reported include antiurolithiatic, hepatoprotective, antioxidant, analgesic, antipyretic, anti-inflammatory, antidiabetic, antihyperlipi-demic and antitumor activity. In the present review the literature data on the phytochemical and biological investigations on the I. frutescens are summarized up to March 2011. |
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| Keywords: | Ichnocarpus frutescens Antitumor Anti-inflammatory Hepatoprotective |
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