某综合医院医院感染病原学分析

目的了解某院医院感染病原学情况，指导临床医院感染的防控工作。方法对该院2012年全部医院感染患者分离的病原体的分布及其耐药情况进行统计分析。结果共检出病原体71种，793株，其中革兰阴性菌504株（63.56%），革兰阳性菌204株（25.72%），真菌85株（10.72%）；大肠埃希菌（129株，16.27%）、肺炎克雷伯菌（121株，15.26%）、鲍曼不动杆菌（100株，12.61%）、金黄色葡萄球菌（79株，9.96%）及铜绿假单胞菌（70株，8.83%）居前5位；菌株来源居前3位的感染部位分别是下呼吸道（323株，40.73%）、血液（116株，14.63%）、泌尿系统（116株，14.63%）。274株医院感染病原菌为多重耐药菌，占全部医院感染病原体的34.55%。结论该院医院感染病原体以革兰阴性菌为主，多重耐药菌所占比例较高，需加强监测和防控。

Analysis on pathogens in healthcare associated infection in a general hospita

ObjectiveTo investigate the pathogens causing healthcare associated infection (HAI) in a hospital, and guide the prevention and control of HAI.MethodsDistribution and antimicrobial resistance of pathogens isolated from patients with HAI in 2012 were analyzed statistically.ResultsA total of 793 isolates of 71 pathogen species were isolated, including 504 isolates (63.56%) of gram negative bacteria，204 (25.72%）of gram positive bacteria, and 85 (10.72%） of fungi; the top five pathogens were Escherichia coli（n=129，16.27%）, Klebsiella pneumoniae（n=121，15.26%）, Acinetobacter baumannii（n=100，12.61%）, Staphylococcus aureus（n=79，9.96%）, and Pseudomonas aeruginosa（n=70，8.83%）， the top three sites of pathogen islation were lower respiratory tract (323,40.73%), blood stream (116.14.63%)， and urinary system (116,14.63%).274(34.55%) pathogens were multidrug resistant organisms.ConclusionThe major pathogens in HAI are gram negative bacteria, most are multidrug resistant strains, monitor should be intensified.