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Transfer of beta-lactamase-associated cefoxitin resistance in Bacteroides fragilis. |
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| Authors: | G J Cuchural Jr F P Tally J R Storey M H Malamy |
| Abstract: | A cefoxitin-resistant Bacteroides fragilis isolate, TAL 4170, which inactivates cefoxitin, was able to transfer beta-lactamase-mediated cefoxitin resistance to a susceptible B. fragilis recipient. Cefoxitin-resistant transconjugants acquired a new beta-lactamase with a pI of 8.1 and were able to inactivate cefoxitin and retransfer cefoxitin resistance. No plasmids were detected in the donor or transconjugants. |
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