| 促智药普拉西坦的合成 |
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| 引用本文： | 关恺珍,卢丽霞.促智药普拉西坦的合成[J].医疗保健器具,2007(12):8. |
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| 作者姓名： | 关恺珍 卢丽霞 |
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| 作者单位： | 广州市第一人民医院,广东广州,510180 |
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| 摘 要： | 氯乙酰氯与N,N-二异丙基乙二胺在碱性条件下进行酰化,所得中间体与2-吡咯烷酮烷基化,得普拉西坦。
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| 关 键 词： | 普拉西坦 2-吡咯烷酮 合成 |
Synthesis of Pramiracetam |
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| Guan Kai zhen,Lu Lixia.Synthesis of Pramiracetam[J].Medicine Healthcare Apparatus,2007(12):8. |
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| Authors: | Guan Kai zhen Lu Lixia |
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| Abstract: | Pramiracetam was prepared by alkylation with 2-oxo-1-pyrrolidine and an intermediate which was synthesized by acylation under alkali conditions with chloracetyl chloride and N,N-bis(1 methylethyl)-1,2-ethylenediamine. |
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| Keywords: | Pramiracetam 2-oxo-1-pyrrolidine synthesis |
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