| 新疆三种阿魏对胃肠道作用的比较 |
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| 引用本文： | 熊元君,刘发,叶尔波,胡坚,杨新忠. 新疆三种阿魏对胃肠道作用的比较[J]. 新疆医科大学学报, 1993, 0(4) |
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| 作者姓名： | 熊元君 刘发 叶尔波 胡坚 杨新忠 |
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| 作者单位： | 新疆中药民族药研究所，新疆医学院基础部药理学教研室，新疆中药民族药研究所，新疆医学院基础部药理学教研室，新疆医学院基础部药理学教研室 |
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| 摘 要： | 本文以胃肠作用为指标,比较新疆三种阿魏的药理作用,探讨乌恰阿魏、多伞阿魏代替新疆阿魏应用的可能性。结果说明,三种阿魏对大鼠应激性胃溃疡和乙酰水杨酸致药物性胃溃疡均有明显的防治作用。在离体肠肌实验中,三种阿魏均抑制兔肠肌的自发蠕动。以半效抑制浓度(IC_(50))为标准,抑制作用强弱依次为多伞阿魏、乌恰阿魏和新疆阿魏。本研究为新疆阿魏治疗消化系统疾病和以乌恰阿魏、多伞阿魏代替新疆阿魏应用提供了药理学依据。
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| 关 键 词： | 阿魏 胃溃疡 乙酰水杨酸 |
Effects of Three Species of Ferula on the Gastroenteric Tract |
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| Xion Yuanjun,et al Institute of Chinese and Uygur Traditional Meteria Medica of Xinjiang. Effects of Three Species of Ferula on the Gastroenteric Tract[J]. Journal of Xinjiang Medical University, 1993, 0(4) |
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| Authors: | Xion Yuanjun et al Institute of Chinese Uygur Traditional Meteria Medica of Xinjiang |
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| Abstract: | Authors studied and compared with the pharmacologic effect of three species of Ferula on the gastroenteric tract of rats. The aim of this study is to research the possibility of use of Ferula conocaula korov, Ferula ferulaeoides(stend.) korov instead of Ferula sinkiangensis K. M. Shen. The results showed: hree Ferula markedly prevent and cure stress ulcers and gastric ulcers induced by aspirin in rat. In the isolated examination, three species of Ferula inhibited spontaneous movement on the duodenum of rabbits. The strong tendency order of half inhibited concentration(IC_(50)) is Ferula ferulaeoides(sted.)korov, Ferula conocaula korov and Ferula sinkiangensis K. M. Shen. It concluded that the result provided their pharmacological proof to cure disease of gastroenteric tract and the possible use of Ferula conocaula korov, Ferula ferulaeoides(sted.) korov instead of Ferula sinkiangensis K. M. Shen. |
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| Keywords: | ferula gastric ulcers aspirin |
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