大蒜素和甲醛甲酚在治疗慢性根尖周炎中的疗效比较

目的：对比研究大蒜素及甲醛甲酚治疗慢性根尖周炎的近期临床疗效。方法：将185颗慢性根尖周炎患牙常规开髓、清理根管后随机分为3组。大蒜素组（94颗牙）于根管口封大蒜素棉球，甲醛甲酚（FC）组（78颗牙）于根管口封FC棉球，生理盐水组（13颗牙）于根管口封生理盐水棉球。观察3 d内各组封药后急性反应发生率等近期临床反应。结果：封药3 d内，3组出现急性反应的比例分别为前牙5.1%，10.7%，50％；后牙5.5%，8.0%，60％。大蒜素组和FC组前牙（P＞0.05）、后牙（P＞0.05）封药后急性反应率比较差异无显著性，大蒜素组和FC组分别与生理盐水组比较，封药后急性反应率差异有显著性（P＜0.05）。结论：大蒜素治疗慢性根尖周炎的近期临床疗效与FC相似，相对于FC的副作用，大蒜素可取代FC。

Garlicin and formocresol in the treatment of chronic periapical periodontitis

Objective To evaluate the short period clinical responses after sealed garlicin and formocresol small cotton ball in the root canal entrance to treat chronic periapical periodontitis.Methods Treatment records of 185 teeth with chronic periapical periodontitis were compared. Of them, 94 teeth were treated by sealed small garlicin cotton ball in the root canal entrance, 78 were treated by sealed small formocresol cotton ball in the root canal entrance,and the other 13 were treated by sealed small normal saline cotton ball. The curative effects were evaluated through clinical observation.Results The ratios of acute reaction in 3 days following sealed garlicin, formocresol and normal saline small cotton ball were 5.1% ,10.7%, and 50% in the anterior teeth,and 5.5%,8.0%,and 60%, in the posterior teeth, respectively .Conclusion The clinical curative effects were similar between garlicin and formocresol in the short period. Formocresol can be substituted by garlicin.