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AIDS-related cholangiopancreatographic changes
Authors:J. Farman  J. Brunetti  J. W. Baer  H. Freiman  G. M. Comer  F. J. Scholz  R. E. Koehler  K. Laffey  P. Green  A. R. Clemett
Affiliation:(1) Department of Radiology, MH3-204, Columbia-Presbyterian Medical Center, 10032-3284 New York, NY, USA;(2) Department of Radiology, St. Luke's-Roosevelt Medical Center, Columbia-Presbyterian Medical Center, 10032-3284 New York, NY, USA;(3) Departments of Medicine and Radiology, St. Vincent's Hospital, 10014 New York, NT, USA;(4) Division of Gastroenterology, Department of Medicine, SUNY at Stony Brook, 11794 Stony Brook, NY, USA;(5) Department of Radiology, Lahey Clinic, 01803 Burlington, MA, USA;(6) Department of Radiology, University of Alabama at Birmingham, 35203 Birmingham, AL, USA;(7) Department of Gastroenterology, Columbia-Presbyterian Medical Center, 10032 New York, NY, USA
Abstract:The cholangiographic and pancreatographic appearances of the acquired immunodeficiency syndrome (AIDS) associated cholangitis were evaluated in 26 patients. Twenty-four patients were diagnosed by retrograde cholangiography or endoscopic cholangiopancreatography (ERC or ERCP). One patient was diagnosed by T-tube cholangiography and another patient by transhepatic cholangiography. The radiographic findings ranged from intrahepatic ductal abnormalities with or without involvement of the extrahepatic biliary tree (eight patients) to irregularities and strictures involving the ampulla of Vater or the intrapancreatic portion of the common bile duct (CBD) with proximal dilatation (18 patients). Significant strictures involving the juxta-ampullary pancreatic duct were identified in six of 12 patients. Twenty-one of the 26 patients had associated infections which included: Cryptosporidium (CS), Mycobacterium avium intracellulare (MAI), cytomegalovirus (CMV), Microsporidium (MSP), and Isospora (ISP). Three patients were operated upon for acute acalculous cholecystitis. In each instance, organisms were identified in both the bile duct and the inflamed gallbladder.An editorial commentary on this article follows on pp. 423–424.
Keywords:AIDS cholangiopancreatitis  Pancreatic duct stricture and dilatation-ampullary stenosis  Intrapancreatic bile duct stricture  IHD and EHD irregularities and strictures  Multiple infections
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