冠状动脉搭桥术中Symmetry主动脉近端吻合器的实验研究

目的利用Symmetry主动脉近端吻合器进行静脉移植物与升主动脉吻合的动物实验,评价其吻合时间、吻合口血流量和通畅率,为临床应用提供科学依据。方法以犬作为实验对象,取自体股静脉作为移植血管,在非体外循环心脏不停跳下完成主动脉至冠状动脉的冠状动脉旁路手术(OPCABG)。以Symmetry主动脉近端吻合器完成的近端吻合口作为实验组(N=10),以5～0Prolene缝线手工缝合的近端吻合口作为对照组(N=10)。测量、比较两组的吻合时间;术中应用多谱勒血流量仪测量吻合口的血流量;静脉内注射新福林提高血压,观察不同压力下吻合口的渗漏。结果实验组吻合时间为98.30士9.63s,对照组为200.50士7.54s,P0.05。实验组所能承受的最大血压平均为180士7.0mmHg,明显高于对照组160士8.0mmHg,P

The Animal Experiment of Dog Model by Symmetry Aortic Proximal Connector in Coronary Artery Bypass Grafting

Objective An animal experiment was carried out to complete proximal anastomosis of vein graft and ascending aorta in CABG with Symmetry Aortic Proximal Connector in dog model. Methods The proximal anastomosis of the OPCABG completed with the Symmetry Aortic Proximal Connector were assigned as the experiment group（N=10）,while the proximal anastomosis manually sutured as the control group（N=10）.The time of completing the anastomosis and the flow through the vein grafts were recorded, The leakage of the anastomosis was identified at different blood pressure levels, which were raised by venous bolus of neosynephrine. Results The anastomotic time consuming of the experiment group was 98.30 ± 9.63 seconds, while the control group was 200.50 ± 7.54 seconds（P〈0.01）. The blood flow through vein graft in experiment group was 12.07 ± 0.60ml/min, and 11.96 ± 0.80 ml/min in control group （P〉0.05）.The blood pressure threshold of anastomosis bleeding were180 ± 7.0mmHg and 160 ± 8.0mmHg in experiment group and control group（P〈0.01）, respectively. Conclusion Symmetry Aortic Proximal Connector is a quick, simple, effective and reliable device for proximal anastomosis of coronary artery bypass surgery.