益气养阴活血方治疗糖尿病肾病30例临床研究

目的：观察益气养阴活血方药治疗糖尿病肾病（DN）的疗效。方法：在常规治疗基础上以益气养阴活血方药治疗DN30例，并设对照组30例进行比较观察。结果：治疗组总有效率（76．7％）明显高于对照组（50％）。治疗组治疗后，尿蛋白排泄率、24小时尿蛋白定量明显减少（P〈0．05或P〈0．01），低密度脂蛋白胆固醇明显降低（P〈0．01）。结论：益气养阴活血方药治疗DN具有调整脂代谢、减少蛋白尿、改善肾功能及主要临床症状、延缓肾功能减退进程等作用。

Clinical Study on the Recipe for Supplementing Qi,Nourishing Yin and Activating Blood Circulation for Treatment of 30 Cases of Diabetic Nephropathy

Objective:To observe therapeutic effect of the recipe for supplementing qi,nourishing yin and activating blood circulation on diabetic nephropathy (DN).Methods:The treatment group (30 cases of DN) was treated with routine treatment plus the recipe for supplementing qi,nourishing yin and activating blood circulation,and the control group (30 cases) was treated with routine treatment of western medicine.Results:The total effective rate of 76.7% in the treatment group was significantly higher than 50.0% in the control group.After treatment,Urine Albumin Excretion Rate(UAER) and 24-hour urinary protein significantly decreased(P<0.05 or P<0.01),low-density lipoprotein-cholesterol significantly decreased(both P<0.05).Conclusion:The recipe for supplementing qi,nourishing yin and activating blood circulation has functions of regulating lipid metabolism,reducing urinary protein,improving renal function and main clinical symptoms,delaying hypofunction of renal function,in treatment of DN.