| 几种常用消毒剂和加热对乙型肝炎表面抗原灭活作用的实验研究 |
| |
| 引用本文： | 吴国强,李荣,许继庄. 几种常用消毒剂和加热对乙型肝炎表面抗原灭活作用的实验研究[J]. 中国消毒学杂志, 1988, 0(1) |
| |
| 作者姓名： | 吴国强 李荣 许继庄 |
| |
| 作者单位： | 中国人民解放军总参谋部卫生处防疫化验室(吴国强，李荣)，中国人民解放军总参谋部卫生处防疫化验室(许继庄) |
| |
| 摘 要： | <正> 乙型肝炎病毒(HBV)至今仍不能进行组织培养,动物模型极少,且来源困难。目前,对HBV消毒试验多以乙型肝炎表面抗原(HBsAg)抗原性消除作为对HBV消毒效果的标志。国内进行此类试验方法尚不统一,故诸结果相差甚大。我们参考胡善联等建立的HBsAg定量检测方法,对几种常
|
EXPERIMENTAL STUDY ON THE INACTIVATION EFFECTS OF SEVERAL COMMON DISINFECTANTS AND HEAT ON HBsAg |
| |
| Abstract: | The inactivation effects of 4 disinfectants and heat on HBsAg were observed in laboratory. HBsAg was quantitatively examined by SPRIA. The results indicated that in order to convert the testing serum into HBsAg negative(P/N<2.1), 2 min was required when the serum was exposed to solution of sodium hypochlorite(containing available chlorine 2,000 mg/L). When peracetic acid was used, 0.8% solution with a 2 min contact time, 0.5% solution with 10 min or 0.2% with 20 min contact was required to inactivate HBsAg. Heat at 98℃ for 1 hr could also bring about negative conversion of the testing serum. Both 95% ethyl alcohol and 1:125 bromogeramine could not completely inactivate HBsAg, but significantly lower its concentration after contact for 30 min. For instance, 70% ethyl alcohol with a 2 min contact time could lower the concentration of HBsAg by 92%. |
| |
| Keywords: | |
| 本文献已被 CNKI 等数据库收录！ |
|
