| 阿罗洛尔——无代谢不良反应的肾上腺素β受体阻滞药 |
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| 引用本文： | 郭冀珍.阿罗洛尔——无代谢不良反应的肾上腺素β受体阻滞药[J].中国新药与临床杂志,2008,27(4):313-316. |
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| 作者姓名： | 郭冀珍 |
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| 作者单位： | 上海交通大学医学院附属瑞金医院,高血压科,上海,200025 |
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| 摘 要： | 阿罗洛尔除具有肾上腺素α、β受体阻滞药共有的抑制交感及扩张血管特点外,在减慢心率作用方面比常用的卡维地洛、拉贝洛尔明显,与肾上腺素β受体阻滞药美托洛尔相近,但无美托洛尔的糖、脂代谢不良反应。在降压方面,尤其适用于中青年舒张期高血压,能有效地减慢心率、降舒张压。
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| 关 键 词： | 肾上腺素能β受体拮抗剂 安全 抗高血压药 中年人 阿罗洛尔 |
| 文章编号： | 1007-7669(2008)04-0313-04 |
| 修稿时间： | 2007年9月15日 |
Arotinolol: a adrenergic beter-blocker without adverse reactcion on metabolism |
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| GUO Ji-zhen.Arotinolol: a adrenergic beter-blocker without adverse reactcion on metabolism[J].Chinese Journal of New Drugs and Clinical Remedies,2008,27(4):313-316. |
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| Authors: | GUO Ji-zhen |
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| Abstract: | Arotinolol demonstrates a common effect of inhibiting sympathetic excitement and dilating the blood vessel which is owned by alpha/beta-adrenergic blocker.In addition to that,it also can lower the heart rate(HR)significantly comparing to carvedilol or labetalol.The effect of HR lowering is close to beta-blocker, metoprolol,without the adverse reactions on glucose and lipid metabolism.In the treatment of hypertension, arotinolol is particularly applicable to middle-aged diastolic hypertension and has effective in slowing HR and lowering the diastolic blood pressure. |
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| Keywords: | adrenergic beta-antagonists safety antihypertensive agents middle aged arotinolol |
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