SQUAMOUS CELL CARCINOMA IN POROKERATOSIS IN TWO PATIENTS |
| |
| Authors: | A Öneill CA Commens S Kossard H Coats |
| |
| Institution: | Skin and Cancer Foundation, Darlinghurst, NSW. |
| |
| Abstract: | Malignancy arising in porokeratoses is a well recognised but infrequently reported complication. Histological studies suggest that malignancy arises from the abnormal clone of keratinocytes which produce the cornoid lamella. We report two cases of squamous cell carcinoma arising in porokeratoses and postulate genetic, environmental and host factors as important in the evolution of their malignancy. |
| |
| Keywords: | Squamous cell carcinoma porokeratosis of Mibelli linear porokeratosis cornoid lamella |
|
