| 高效液相色谱法测定尿毒清胶囊中芍药苷的含量 |
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| 引用本文： | 李晓冰,郭旭东. 高效液相色谱法测定尿毒清胶囊中芍药苷的含量[J]. 黑龙江医药, 2012, 25(1): 13-14 |
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| 作者姓名： | 李晓冰 郭旭东 |
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| 作者单位： | 1. 哈药集团三精明水药业有限公司 黑龙江明水151700
2. 内蒙扎兰屯市中蒙医院 黑龙江明水151700 |
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| 摘 要： | 目的:用高效液相色谱法测定尿毒清胶囊中芍药苷含量。方法:色谱柱AgilentC18(4.6×250mm),流动相为乙腈-0.1%磷酸溶液(20:80),流速为1mL/min,检测波长230nm。结果:芍药苷0.080μg～0.722μg范围内呈良好的线性关系,回归方程为Y=696000X+6590(r=0.9998),平均回收率为100.05(RSD=0.67%)。结论:本方法简便、结果准确,能有效控制尿毒清胶囊的质量。
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| 关 键 词： | 高效液相色谱法 尿毒清胶囊 芍药苷 含量测定 |
Determination of Paeoniflovin in Niaoduqing Capsules by HPLC |
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| Affiliation: | Li Xiaobing Sanjing Mingshui Pharmaceutical Chemical Co. ,Ltd of Harbin Pharm. Group( Heilogjiang ,Mingshui, 151700) |
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| Abstract: | Objective：To determine the content of paeoniflovin in Niaoduqing Capsules by HPLC. Methods：The determination was carried out with AgilehtCls column （4. 6 x 250mm）. The mobile phase consisted of acetonitrile water （ contain 0. 01% phosphoril acid）. The flow rate was 1 mL · min-1 and the detective wavelength was 230 nm. Results：The calibration curve for paeoniflovin was linear in the range of 0. 0801xg -0. 722 ug, the regression equation was Y = 696000X ＋ 6590 （r = O. 9998） ,and the mean recovery was 100. 05% ,RSD was 0. 67%. Conclusion：This method is simple and accurate and can be used for the quality control of Niaoduqing Capsules. |
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| Keywords: | HPLC Niaoduqing Capsules paeoniflovin content determination |
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