Occult hepatitis B in blood donors in Indonesia: altered antigenicity of the hepatitis B virus surface protein期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Occult hepatitis B in blood donors in Indonesia: altered antigenicity of the hepatitis B virus surface protein

Authors:	Meta D. Thedja Martono Roni Alida R. Harahap Nurjati C. Siregar Susan I. Ie David H. Muljono

Affiliation:	(1) Eijkman Institute for Molecular Biology, Jl. Diponegoro 69, Jakarta, Indonesia;(2) Faculty of Medicine, University of Indonesia, Jl. Salemba 6, Jakarta, Indonesia;

Abstract:	Background and aims Occult hepatitis B virus infection (OBI) poses a challenge to the safety of blood donation. The prevalence of OBI is not well documented in Indonesia, although this information in such an endemic country is needed. This study was aimed to evaluate the prevalence of occult hepatitis B in blood donors from two cities of Indonesia, and to study the genetic variation and its effect on the predicted antigenicity of HBsAg.

Keywords:	Hepatitis B Hepatitis B virus HBV Occult hepatitis B OBI Antigenic index Antigenic property Blood donor
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