血清前白蛋白联合降钙素原、C 反应蛋白对颅脑外伤术后并发肺部感染的诊断价值

目的 探讨血清前白蛋白（PA）、C反应蛋白（CRP）、降钙素原（PCT）对颅脑外伤术后并发肺部感染的诊断价值。方法 回顾性分析2017年2月至2022年2月中国人民解放军联勤保障部队第九〇四医院常州医疗区收治的80例脑外伤术后患者的临床资料，根据是否并发肺部感染将其分为并发组（18例）与未并发组（62例）。比较两组一般资料及血清PA、CRP及PCT水平，logistic回归分析颅脑外伤术后并发肺部感染的影响因素，受试者操作特征（ROC）曲线分析诊断价值。结果 并发组有吸烟史占比、有肺部疾病史占比及CRP、PCT水平均高于未并发组，血清PA低于未并发组（P<0.05）；多因素logistic回归分析显示，吸烟史（OR=4.651,95%CI:1.829～11.822）、肺部疾病史（OR=4.791,95%CI:1.591～12.405）、血清PA(OR=0.274,95%CI:0.097～0.776)、血清PCT(OR=3.854,95%CI:1.665～8.916)、血清CRP(OR=4.671,95%CI:1.887～9.172)均是颅脑外伤术后并发肺部感染的影响因素（P<...

Diagnostic value of serum prealbumin combined with procalcition and C- reactive protein for infection after surgery for traumatic brain injury

Objective To explore the diagnostic value of serum prealbumin (PA), C-reactive protein (CRP), and procalcition (PCT) in patients with lung infection after surgery for traumatic brain injury. Methods A retrospective analysis was conducted on the clinical data of 80 postoperative patients with brain injury admitted to the Changzhou Medical District of the No. 904 Hospital of the Joint Logistics Support Force of the Chinese People’s Liberation Army from February 2017 to February 2022. They were divided into concurrent group (18 cases) and non concurrent group (62 cases) according to whether they have pulmonary infection. The basic data and serum levels of PA, CRP, and PCT were compared between the two groups. Logistic regression analysis was used to identify the influencing factors for postoperative pulmonary infection in patients with brain injury, and receiver operator characteristic (ROC) curve analysis was used to assess the diagnostic value. Results The proportion of concurrent group with a smoking of history, lung disease history, and the levels of CRP and PCT in the concurrent group were higher than those in the non concurrent group, while the serum PA was lower than that in the non concurrent group (P＜0.05); multiple logistic regression analysis showed that smoking (OR=4.651, 95%CI= 1.829-11.822), history of lung disease (OR=4.791, 95%CI：1.591-12.405), serum PA (OR=0.274, 95%CI：0.097-0.776), serum PCT (OR=3.854, 95%CI：1.665-0.916), and serum CRP (OR=4.671, 95%CI：1.887-9.172) were all influencing factors for pulmonary infection in patients with traumatic brain injury (P＜0.05); the ROC analysis showed that serum PA, CRP, and PCT levels can be used to evaluate postoperative pulmonary infection in patients with traumatic brain injury. The areas under the curve were 0.943, 0.920, and 0.817, respectively (P＜0.05). Conclusion The levels of serum PA, PCT, and CRP are closely related to pulmonary infection after surgery for traumatic brain injury, and the detection of these indicators can assist in evaluating the risk of pulmonary infection after surgery for traumatic brain injury.