术前肠内营养支持对低肺功能食管癌患者呼吸功能的影响

【摘要】目的 探讨术前肠内营养支持对低肺功能食管癌患者呼吸功能的影响。方法 56例低肺功能食管癌患者，符合术前最大通气量(MVV)占预测值≤0.5，第1秒用力呼气容积(FEV1)/用力肺活量(FVC)≤0.7，随机分为营养组和对照组各28例。营养组入院后给予肠内营养制剂能全力，对照组给予等热卡量日常饮食。2组给予相同常规护理。2周后比较2组患者肺功能和血气分析指标。结果 营养组治疗后FVC、FEV1、MVV、p（O2）、p（CO2）较治疗前均显著改善（P ＜0.05），但FEV1/FVC差异无统计学意义（P ＞0.05）。对照组各项指标治疗前后差异均无统计学意义（P ＞0.05）。营养组较对照组治疗后FVC、FEV1、MVV、p（O2）、p（CO2）均显著改善（P ＜0.05），但FEV1/FVC差异无统计学意义（P ＞0.05）。结论 术前肠内营养支持能显著提高低肺功能食管癌患者的呼吸功能，为围手术期治疗提供必要支持。

Preoperative enteral nutrition support treatment on the respiratory function of esophageal cancer patients with low pulmonary function

Abstract Objective:To explore the preoperative enteral nutrition support treatment on the respiratory function of esophageal cancer patients with low pulmonary function. Methods:Choose 2011 1 to 12 56 patients with low pulmonary function and esophageal cancer, according with the maximum voluntary ventilation（MVV） was less than 0.5 and the ratio of the first one second to forced vital capacity （FEV1） in the forced expiratory volume (FVC)was less than 0.7，were randomly divided into nutrition group （28patients）and control group （28 patients）. The nutrition group patients were given enteral nutrition supportment and the control group patients were given equal amount of calorie daily diet.Both groups were given the same routine care. After two weeks compared two sets of patients with pulmonary function and arterial blood gas.Results: The values of FVC, FEV1, MVV, arterial partial pressure of oxygen（PaO2）, arterial partial pressure of carbon dioxide（PaCO2） were significantly improved after treatment, the difference was statistically significant (P < 0.05), but FEV1/ FVC difference was not statistically significant (P > 0.05)。 The control group index was also improved, but the difference was not statistically significant (P > 0.05). Compared with the control group the values of FVC、FEV1、MVV、PaO2 and PaCO2 were significantly improved in the nutrition group (P < 0.05), but no significant difference in the level of FEV1/FVC between two groups of patients(P > 0.05). Conclusion:Preoperative enteral nutrition support can significantly improve the low pulmonary function with esophageal cancer patients of respiratory function, to provide perioperative treatment the necessary supportment.