Associations of Peritoneal Glucose Load With Male Sexual Dysfunction and Depression in Peritoneal Dialysis Patients |
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| Authors: | Kamal Hassan Yotam Elimeleh Mona Shehadeh Fadi Hassan Irina Rubinchik |
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| Institution: | 1. Faculty of Medicine in the Galilee, Bar‐Ilan University, Safed, Israel;2. Department of Nephrology and Hypertension, Galilee Medical Center, Nahariya, Israel;3. Biochemistry Laboratory, Galilee Medical Center, Nahariya, Israel;4. Internal Medicine Department E, Galilee Medical Center, Nahariya, Israel |
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| Abstract: | This cross‐sectional study examined possible associations of peritoneal glucose load with male sexual dysfunction and depression in peritoneal dialysis patients. Compared to patients with peritoneal glucose load ≤3 g/kg per day, those with load >3 g/kg per day had higher Beck Depression Inventory scores, (18.9 ± 5.4 vs. 11.4 ± 5.8, P = 0.002) and lower International Index of Erectile Function scores, serum total testosterone and DHEA (15.4 ± 6.4 vs. 45.1 ± 20.7, P < 0.001), (8.5 ± 3.0 vs. 13.9 ± 3.2, P < 0.001), (113.9 ± 58.8 vs. 280.2 ± 128.3, P < 0.001); respectively)]. Of participants with peritoneal glucose load >3 g/kg per day, 84.6% had mild to moderate erectile dysfunction and 92.3% had abnormal Beck Depression Inventory scores. Peritoneal glucose load inversely correlated with International Index of Erectile Function scores (P < 0.001), total serum testosterone (P = 0.002) and serum DHEA (P = 0.001); and directly with Beck Depression Inventory scores (P < 0.001) and serum estradiol (P < 0.001). This study demonstrated higher prevalence of sexual dysfunction, depression and sex hormone disturbances in male peritoneal dialysis patients receiving higher peritoneal glucose load. |
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| Keywords: | Beck Depression Inventory score Erectile dysfunction International Index of Erectile Function score Peritoneal glucose load Sex hormones |
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