痰热清联合抗菌药物治疗医院获得性肺炎的临床观察

目的:观察痰热清注射液联合哌拉西林钠和阿米卡星治疗医院获得性肺炎的效果。方法:104例医院获得性肺炎患者随机均分成2组,治疗组给予痰热清注射液+哌拉西林钠+阿米卡星,对照组给予哌拉西林钠+阿米卡星治疗7～10d,观察用药后2组总有效率、主要症状、体征、X线胸片等临床指标的改善情况。结果:治疗组与对照组总有效率分别为86.54%、67.31%(P<0.05),治疗组在改善体温、呼吸困难、口罗音及X线胸片方面优于对照组(P<0.05或P<0.01或P<0.001)。结论:痰热清注射液联合哌拉西林钠和阿米卡星治疗医院获得性肺炎安全、有效。

Tanreqing Injection in Combination with Antibacterials for Hospital-acquired Pneumonia

OBJECTIVE:To observe the therapeutic effect of Tanreqing injection in combination with Piperacillin sodium and Amikacin sulfate for hospital-acquired pneumonia.METHODS:104 cases of hospital-acquired pneumonia were enrolled and randomly assigned to receive Tanreqing Injection+Piperacillin Sodium+Amikacin Sulfate(treatment group,n=52) or Piperacillin Sodium+Amikacin sulfate(control group,n=52) for 7～10days.The clinical indexes including the total effective effect,cardinal symptoms,physical signs,and chest X-ray film in two groups after treatment were observed.RESULTS:The total effective rate in the treatment group was 86.54% as compared 67.31% in control group(P<0.05).The treatment group showed more effective amelioration than control group in clinical indexes including body temperature,dyspnoea,rales and chest X-ray film(P<0.05 or P<0.01 or P<0.001).CONCLUSION:Tanreqing injection combined with Piperacillin sodium and Amikacin sulfate is safe and effective for hospital-acquired pneumonia.