Amplitude change with click rate in human brainstem auditory-evoked responses

The effect of click rate on wave amplitude of human brainstem auditory-evoked response (BAER) was examined at repetition rates of 10, 30, 50, 70 and 90 Hz in 80 healthy children aged 1 month to 6 years and in 21 adults. As repetition rate was increased from 10 to 90 Hz at 70 dB HL, the amplitudes in different age groups decreased by 33-45% (0.109-179 microV) for wave I and 25-41% (0.055-0.145 microV) for wave V. The older the children, the larger the absolute decrements of wave amplitudes with increasing repetition rate, but the relative decrements or reduction rates of wave amplitudes exhibited no systematically age-related differences. The V/I amplitude ratio tended to increase with increasing repetition rate in most age groups, suggesting that the amplitude of wave I is affected by the repetition rate slightly more than that of wave V. The patterns of the changes in wave amplitudes with repetition rate at lower intensity levels were essentially similar.