北京市海淀区三所高校在职教职工胃食管反流病流行病学调查

目的了解北京市海淀区高校在职教职工胃食管反流病（GERD）的患病状况,探讨GERD发生的危险因素。方法 2008年10~12月,采用方便抽样方法 ,使用＂中国胃食管反流病协作组＂推荐的反流性疾病问卷（reflux diagnostic questionnaire,RDQ）对海淀区三所高校在职教职工进行GERD抽样调查,并对调查结果统计分析。采用SPSS 13.0软件对危险因素进行χ2检验,多因素logistic回归分析,P〈0.05为差异有统计学意义。结果海淀区三所高校在职教职工GERD的患病率为0.69%,典型症状发生率为9.57%,单纯症状者占8.88%。运用χ2检验、多因素logistic统计方法 ,被调查人群的健康状态、生活压力、胃肠道疾病和胃肠肿瘤家族史对GERD患病率影响具有统计学意义。结论与普通人群相比,海淀区高校在职教职工人群GERD患病率相对较低,典型症状发生率相差不大,但单纯症状的发生率较高。健康状态、生活压力以及胃肠道疾病和胃肠肿瘤家族史为GERD的危险因素。

An epidemiological survey of gastroesophageal reflux disease in university faculties in Haidian district,Beijing

Objective To investigate the prevalence of gastroesophageal reflux disease（GERD） and identify the risk factors in university faculties in Haidian District,Beijing.Methods From October to December 2008,a survey of GERD was conducted in the faculties of three universities in Haidian district with a standard sampling method recommended by Chinese Gastroesophageal Reflex Disease Collaborative Group.The collected data were analyzed for the associated factors of the disease with χ2 test and multiple variable logistic analysis.Results The prevalence rate of CERD was 0.69% for the faculties of three universities in Haidian district.9.57% of participants reported with typical symptoms and 8.88% of them reported with single symptom.The statistical analysis suggested that the GERD was associated with health status,life stress,family history of gastrointestinal disease and gastrointestinal cancer.Conclusion The university faculties of Haidian district had a relatively low prevalence rate of GERD,although a similar and high proportion of participants had typical symptoms and reported single suspect symptom,respectively.GERD was associated with health status,life stress and the family history of gastrointestinal disease and gastrointestinal cancer.