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外用咪喹莫特对尖锐湿疣激光术后复发的预防作用
引用本文:马殷浩,张庆江,朱宇翔.外用咪喹莫特对尖锐湿疣激光术后复发的预防作用[J].中国临床药学杂志,2006,15(1):27-28.
作者姓名:马殷浩  张庆江  朱宇翔
作者单位:1. 浙江省海宁市人民医院药剂科,海宁,314400
2. 浙江省嘉兴市第一医院皮肤性病科,嘉兴,314000
摘    要:目的观察咪喹莫特乳膏局部外用预防尖锐湿疣激光术后复发的效果。方法将107例尖锐湿疣患者随机分成2组,治疗组在CO2激光术后局部外用咪喹莫特乳膏8 wk,对照组单纯用CO2激光治疗,随访6 mo,观察2组患者有无疣体复发。结果随访6 mo,治疗组的复发率为12.50%,对照组的复发率为45.10%(P<0.01)。结论咪喹莫特乳膏局部外用对尖锐湿疣激光术后复发具有预防作用。

关 键 词:咪喹莫特  尖锐湿疣  CO2激光  复发
文章编号:1007-4406(2006)01-0027-02
收稿时间:2005-03-04
修稿时间:2005-03-04

Effect of imiquimod cream on preventing recurrence of condyloma acuminatum following laser treatment
Ma Yinhao,Zhang Qingjiang,Zhu Yuxiang.Effect of imiquimod cream on preventing recurrence of condyloma acuminatum following laser treatment[J].Chinese Journal of Clinical Pharmacy,2006,15(1):27-28.
Authors:Ma Yinhao  Zhang Qingjiang  Zhu Yuxiang
Abstract:AIM To observe the effect of imiquimod 5% cream for topical application on preventing recurrence of condyloma acuminatum after CO_2 laser treatment.METHODS One hundred and seven patients of condyloma acuminatum were randomized into 2 groups: treatment group and control group.The treatment group(n=56) was treated with imiquimod 5% cream topically for 8 wk after CO_2 laser therapy. Control group(n=51) was treated with CO_2 laser therapy only.All cases were followed-up for 6 mo to observe the recurrence of wart.RESULTS After 6 mo,the recurrence rate was 12.50% in the treatment group and 45.10% in the control group(P< 0.01).CONCLUSION Using imiquimod 5% cream topically is effective in prevention of condyloma acuminatum relapse after CO_2 laser treatment.
Keywords:imiquimod  condyloma acuminatum  CO_2 laser  recurrence
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