原发性肝癌转化治疗及其维持治疗策略

肝癌首选治疗方法为手术治疗,也是惟一能使病人获得长期生存甚至治愈的方法.但我国绝大多数肝癌病人在确诊时已处于中晚期,失去了手术机会.转化治疗是将不可切除的晚期肝癌或者潜在可切除转化为可根治性切除,故成为晚期肝癌治疗研究的热点.转化治疗的常用方法如下:(1)局部治疗,如肝动脉栓塞化疗(TACE)、经肝动脉放疗栓塞(TAR...

Conversion therapy and maintenance therapy for primary liver cancer

The preferred treatment for hepatocellular carcinoma(HCC)is surgery,which is the only way to achieve long-term survival and even a cure. However,the vast majority of liver cancer patients in China are already in the middle and advanced stage of diagnosis and have lost the opportunity of operation. Conversion therapy is to transform unresectable advanced liver cancer or potentially resectable liver cancer into resectable cases,so it has become a hot spot in the treatment of advanced liver cancer. Common methods of conversion therapy are as follows:1.Local treatment:TACE,TARE, HAIC;2.Systemic treatment: targeted therapy combined with immunotherapy;3.Therapeutic alliance:TACE combined with radiation therapy,TACE combined with targeted therapy,HAIC combined with targeted therapy,HAIC combined with targeted therapy and immunotherapy.According to the outcome of conversion therapy, the maintenance treatment plan after conversion therapy is determined,so that patients can obtain the best survival benefit.