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一种银离子过氧化氢手消毒液消毒性能的研究
引用本文:肖湘谊,潘宣合,段文欣,邓宏远,王鹏波,江从元,陈利玉,郑丛龙. 一种银离子过氧化氢手消毒液消毒性能的研究[J]. 中国消毒学杂志, 2021, 38(2): 95-98. DOI: 10.11726/j.issn.1001-7658.2021.02.005
作者姓名:肖湘谊  潘宣合  段文欣  邓宏远  王鹏波  江从元  陈利玉  郑丛龙
作者单位:安信生物科技有限公司;中南大学基础医学院
摘    要:目的 研究一种银离子过氧化氢手消毒液的消毒性能及安全性.方法 采用悬液定量杀菌试验和动物试验方法,对该消毒液杀灭微生物的效果和安全性进行观察.结果 该消毒液中银离子含量为100 mg/L,过氧化氢含量为质量分数0.752%.以该消毒液原液作用0.5 min,对悬液内金黄色葡萄球菌和大肠杆菌的杀灭对数值均>5.00,对悬...

关 键 词:银离子  过氧化氢  手消毒液  杀菌效果  毒性

Study on the disinfection performance of a silver ion hydrogen peroxide hand sanitizer
XIAO Xiang-yi,PAN Xuan-he,DUAN Wen-xin,DENG Hong-yuan,WANG Peng-bo,JIANG Cong-yuan,CHEN li-yu,ZHENG Cong-long. Study on the disinfection performance of a silver ion hydrogen peroxide hand sanitizer[J]. Chinese Journal of Disinfection, 2021, 38(2): 95-98. DOI: 10.11726/j.issn.1001-7658.2021.02.005
Authors:XIAO Xiang-yi  PAN Xuan-he  DUAN Wen-xin  DENG Hong-yuan  WANG Peng-bo  JIANG Cong-yuan  CHEN li-yu  ZHENG Cong-long
Affiliation:(Anson Biological Technology Co.,Ltd.,Changsha Hunan 4103292 School of Basic Medical Sciences,Central South University,China)
Abstract:Objective To study the disinfection performance and safety of a silver ion hydrogen peroxide hand sanitizer.Methods Using suspension quantitative sterilization test and animal test methods,the effect and safety of a certain silver ion hydrogen peroxide disinfectant in killing microorganisms were observed. Results The silver ion content of the silver ion disinfectant was 100 mg/L and the hydrogen peroxide content was 0. 752%( w/w). With the disinfectant stock solution acting for 0. 5 min,the killing logarithmic values of Staphylococcus aureus and Escherichia coli in suspension were both> 5. 00,that of Candida albicans in suspension was > 4. 00. It had obvious killing effect on Influenza virus,Parainfluenza virus and Newcastle disease virus. Using the stock solution of the disinfectant for wipe disinfection for 1 min,the killing logarithmic value of natural bacteria on hand > 1. 00. The LD50 of mouse acute oral toxicity test of this disinfectant was> 5 000 mg/kg body weight. The irritation index of the stock solution for intact skin of rabbits was 0,and it had no micronucleus effect on mouse bone marrow polychromatic erythrocytes. Conclusion The hand sanitizer can quickly kill bacterial propagators,fungi and viruses,and it is a non-toxic substance.
Keywords:silver ion  hydrogen peroxide  hand sanitizer  bactericidal effect  toxicity
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