乳腺囊性增生病不同治疗方法临床疗效观察

目的观察乳腺囊性增生病（CHB）不同治疗方法的临床疗效。方法将235例CHB患者随机分成两组：乳疾灵胶囊组129例（疏肝、活血配伍去痰化湿法）,乳块消胶囊组106例（疏肝活血法）,分别给予药物治疗。将乳疾灵胶囊组随机分为持续性用药组（A组）63例,连续口服乳疾灵胶囊,月经期停药;周期性用药组（B组）66例,月经前两周用药,经期停药。乳块消胶囊组单用乳块消胶囊。全程治疗观察时间为3个月经周期。结果乳疾灵胶囊组总有效率（79.8%）显著高于乳块消胶囊组（49.1%）。A组与B组比较差异无统计学意义。结论治疗CHB配伍祛痰化湿效果明显优于单独疏肝活血法;经前两周周期性用药与持续用药疗效比较差异无统计学意义。

Clinical effects of different treatment methods on cystic hyperplasia of breast

Objective To observe the clinical effects of different treatment methods on cystic hyperplasia of breast.Methods Two hundred and thirty-five patients with cystic hyperplasia of breast were randomly divided into Rujiling capsule group（n=129）and Rukuaixiao capsule group（n=106）.The Rujiling capsule group was further divided into group A（n=63）and group B（n=66）.The patients of group A were orally treated with Rujiling capsule daily except during the menstruation.The patients in group B were treated with Rujiling capsule for two weeks before the menstruation,and stop taking medicine during the menstruation.All the patients were treated for 3 menstrual cycles.Results The effective rate of Rujiling capsule（79.8%）was significantly higher than that of Rukuaixiao capsule group（49.1%）.No statistic differences in effective rate were observed between group A and group B.Conclusion Treatment effects of Rujiling capsule on cystic hyperplasia of breast is significantly superior to that of Rukuaixiao capsule.No significant differences were observed on effects between different treatment measures of Rujiling capsule（drug administrated for two weeks before the menstruation or continuously）.