| 环磷酰胺冲击疗法联合小剂量皮质类固醇治疗狼疮性肾炎 |
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| 引用本文： | 胡萍,成于珈,谷沅珉. 环磷酰胺冲击疗法联合小剂量皮质类固醇治疗狼疮性肾炎[J]. 中华皮肤科杂志, 1999, 32(1): 14-16 |
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| 作者姓名： | 胡萍 成于珈 谷沅珉 |
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| 作者单位： | 湖北医科大学附属第一医院皮肤科 |
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| 摘 要： | 目的 探讨环磷酰胺冲击疗法联合小剂量皮质类固醇激素治疗狼疮性肾炎的疗效。方法 对３４例 狼疮性肾炎患者使用环磷酰胺冲击疗法联合小剂量皮质类固醇激素治疗，并与２５例单用皮质类固醇激素疗法进行对照观察。结果 环磷酰胺冲击疗法联合小剂量皮质类固醇激素疗法组的临床症状及免疫学指标的改善，肾功能的改善及肾衰率的降低均明显优于单用激素疗法组，且不良反应不大。结论 环磷酰胺冲击疗法联合小剂量皮质类固醇激素治疗狼
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| 关 键 词： | 狼疮性肾炎 环磷酰胺 皮质类固醇 冲击疗法 |
Clinical Evaluation on Cyclophosphamide Pulse Therapy in Combination with Small Dose of Corticosteroid for the Treatment of Lupus Nephritis |
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| HU Ping,CHENG Yujia,GU Yuanmin. Clinical Evaluation on Cyclophosphamide Pulse Therapy in Combination with Small Dose of Corticosteroid for the Treatment of Lupus Nephritis[J]. Chinese Journal of Dermatology, 1999, 32(1): 14-16 |
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| Authors: | HU Ping CHENG Yujia GU Yuanmin |
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| Affiliation: | HU Ping,CHENG Yujia,GU Yuanmin,Department of Dermatology,First Affiliated Hospital,Hubei Medical University,Wuhan 430060 |
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| Abstract: | Objective To evaluate the effectiveness of cyclophosphamide pulse therapy in combination with small dose of corticosteroid for the treatment of lupus nephritis Methods Thirty four patients with lupus nephritis were treated by cyclophosphamide pulse therapy in combination with small dose of corticosteroid, compared with 25 cases of lupus nephritis treated by conventional corticosteroid therapy Results The combination therapy had better results than those of conventional corticosteroid therapy, including the improvement of the clinical manifestations, immunological indexes, renal functions, decreasing of incidence of renal failure and the frequency of side effects Conclusion Combination therapy has a better effectiveness in treating lupus nephritis |
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| Keywords: | Lupus nephritis Cyclophosphamide Corticosteroid |
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