| 补虚散结胶囊对小鼠Lewis肺癌细胞增殖动力学的影响 |
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| 引用本文： | 后盾,刘望姣,高允珊,李宏良,邱侠,杨怀新,杨振江. 补虚散结胶囊对小鼠Lewis肺癌细胞增殖动力学的影响[J]. 河北中医药学报, 2007, 22(2): 10-11 |
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| 作者姓名： | 后盾 刘望姣 高允珊 李宏良 邱侠 杨怀新 杨振江 |
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| 作者单位： | 广东省深圳市中医院,深圳,518001;广州中医药大学 |
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| 摘 要： | 目的:观察补虚散结胶囊对肺癌瘤株Lewis肺癌细胞增殖动力学的影响,探讨补虚散结胶囊治疗肺癌疗效机理。方法:用血清药理学方法进行增效试验,MTT法检测A590值,以每组测得光密度平均值作为药物效应值。结果:补虚散结胶囊配合替加氟组Lewis肺癌细胞存活率低于单纯替加氟组。结论:补虚散结胶囊配合化疗疗效满意,其疗效机理与补虚散结胶囊抑制肿瘤细胞增殖有关。
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| 关 键 词： | 补虚散结胶囊 小鼠Lewis肺癌瘤株 增殖动力学 |
| 文章编号： | 1007-5615（2007）02-0010-02 |
| 收稿时间： | 2005-09-14 |
| 修稿时间： | 2005-09-14 |
Effect of Buxu Sanjie Capsule on Multiplication Dynamics of Lewis Cells of Mice with Lung Cancer |
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| HOU Dun LIU Wang-jiao GAO Yun-shan et al Shenzhen TCM Hospital,Guangdong Province. Effect of Buxu Sanjie Capsule on Multiplication Dynamics of Lewis Cells of Mice with Lung Cancer[J]. Journal of Hebei Traditional Chinese Medicine and Pharmacology, 2007, 22(2): 10-11 |
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| Authors: | HOU Dun LIU Wang-jiao GAO Yun-shan et al Shenzhen TCM Hospital Guangdong Province |
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| Affiliation: | Shenzhen 518001 |
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| Abstract: | Objective: to observe theeffect of Buxu Sanjie Capsule on multiplication dynamics of Lewis cells of mice with lung cancer, and to discuss its curative mechanismin treating lung cancer. Methods: Serum pharmacologywas used to conduct synergia experiment, MTT to examine A590 withthe average optical density as drug effector. Results: survival rate of Lewis cells in Buxu Sanjie Capsuleand Tegafur group was lower than that in pure Tegafur group. Conclusion:Buxu Sanjie Capsule in addition to chemotherapyhas better curative effect, whose mechanism may be relevant to its inhibiting multiplication of tumor cells. |
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| Keywords: | Buxu Sanjie Capsule Lewis cells of lung cancer multiplication dynamics |
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