| 2型糖尿病的全基因组关联研究进展 |
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| 引用本文： | 陆凤,钱云,沈洪兵. 2型糖尿病的全基因组关联研究进展[J]. 疾病控制杂志, 2012, 16(11): 989-994 |
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| 作者姓名： | 陆凤 钱云 沈洪兵 |
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| 作者单位： | 1. 南京医科大学公共卫生学院流行病与卫生统计学系,江苏南京,210029
2. 南京医科大学公共卫生学院流行病与卫生统计学系,江苏南京210029;无锡市疾病预防控制中心健康促进部,江苏无锡214023 |
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| 基金项目： | 国家自然科学基金（81072379）;无锡市科技项目（CSE01016） |
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| 摘 要： | 2型糖尿病是环境和遗传因素共同作用的结果,遗传因素的研究在2006年以前主要是基于连锁分析和候选基因策略,近年来全基因组关联研究的出现使2型糖尿病遗传易感性的研究进入了一个崭新的阶段,发现了很多新的易感基因或区域,为其病因学研究及防治提供新的思路.
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| 关 键 词： | 糖尿病,2型 基因组 研究 疾病遗传易感性 |
Progress in genome-wide association study of type 2 diabetes |
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| LU Feng,QIAN Yun,SHEN Hong-bing. Progress in genome-wide association study of type 2 diabetes[J]. Chinese Journal of Disease Control and Prevention, 2012, 16(11): 989-994 |
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| Authors: | LU Feng QIAN Yun SHEN Hong-bing |
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| Affiliation: | 1. Department of Epidemiology and Biostatistics, School of Public Health, Nanfing Medical University, Nanfing 210029, China; 2. Department of Health Promotion, Wuxi Center for Disease Control and Prevention, Wuxi 214023, China |
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| Abstract: | Type 2 diabetes is the result of both environmental and genetic factors. Before 2006, the study of genetic factors was based on linkage analysis and candidate gene strategy, but it was very slow and difficult. With the emergence of genome-wide association study, the researches on genetic susceptibility of type 2 diabetes have entered a new phase, and found a lot of new susceptibility genes or regions, thereby provide new ideas for the cause of type 2 diabetes and prevention. |
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| Keywords: | Diabetes mellitus, type 2 Genome Research Genetic predisposition to disease |
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