板层角膜移植术治疗带状角膜病变的临床研究

目的:探讨板层角膜移植术对带状角膜病变的治疗效果。方法:2003-01/2008-01我院角膜病组收治带状角膜病变患者16例(16眼)。其中男12例(12眼),女4例(4眼),年龄20～55岁,病史3～20a,患眼视力为光感～0.1不等。手术方法:根据病变的范围,选择不同直径环钻切除病灶,10-0的尼龙线间断缝合等大的植片和植床。结果:术后1wk内,植片可轻度水肿,之后渐变清亮,术后观察6mo～5a,未见病变复发及发生排斥反应者。术后视力均有明显提高,术后6mo,视力≥0.5者3眼,0.1～0.5者11眼,指数～0.1者2眼。结论:板层角膜移植术可以控制带状角膜病变病情发展,提高患眼视力,远期疗效稳定,是治疗带状角膜病变安全有效的疗法。

Clinical research in the treatment of band-shaped keratopathy by lamellar keratoplasty

AIM:To investigate the treatment effect of lamellar keratoplasty on band-shaped keratopathy.·METHODS:Sixteen cases (16 eyes) between January 2003 to January 2008,in which 12 cases (12 eyes) were male and 4 cases (4 eyes) were female,aged from 20 to 55 years old,were included.The time of the disease was between 3 and 20 years.The visual acuity was between light perception and 0.1.According to the range of the disease,an annular-shaped ectatic lesion was defined and removed,and donor tissue of the same size and shape was sutured on the recipient bed with 10- 0 nylon.·RESULTS:There was a little edema in cornea in one week,and then became clarity.No rejections and complications occurred between 6 months and 5 years of follow up.The visual acuity improved obviously.After lamellar keratoplasty 6 months,the visual acuity was>0.5 in 3 eyes,0.1-0.5 in 11 eyes,and <0.1 in 2 eyes.·CONCLUSION:We have developed a safe,successful,and simple procedure for repairing the severe peripheral marginal ectasia in band-shaped keratopathy.This technique substantially improved visual acuity.·