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Development of a compact MRI system for trabecular bone microstructure measurements of the distal radius.
Authors:Shinya Handa  Sadanori Tomiha  Tomoyuki Haishi  Katsumi Kose
Affiliation:Institute of Applied Physics, University of Tsukuba, Tsukuba, Japan. handa@mrlab.frsc.tsukuba.ac.jp
Abstract:A compact MRI system for trabecular bone (TB) microstructure measurements of the distal radius was developed using a 1.0 T permanent magnet and a compact MRI console. TB microstructure of the distal radius was clearly visualized using a three-dimensional (3D) driven equilibrium spin-echo (DESE) sequence in 23 min. The image obtained had a sufficient spatial resolution (150 microm x 150 microm x 500 microm) and signal-to-noise ratio (SNR) (approximately 10) for 3D bone microstructure analysis. The system demonstrated the feasibility of using a permanent magnet compact MRI system as a clinical instrument for bone microstructure measurements of the distal radius.
Keywords:dedicated MRI  distal radius  trabecular bone  bone microstructure  driven equilibrium spin‐echo.
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