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HMGB1 is an independent predictor of death and heart transplantation in heart failure |
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| Authors: | H. C. Volz D. Laohachewin D. Schellberg A. R. Wienbrandt M. Nelles C. Zugck Z. Kaya H. A. Katus M. Andrassy |
| Affiliation: | (1) Department of Internal Medicine III, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany;(2) Department of Internal Medicine II, University of Heidelberg, Heidelberg, Germany; |
| Abstract: | BackgroundHigh-Mobility-Group Box 1 (HMGB1) has been established as an important mediator of myocardial inflammation and associated with progression of heart failure (HF). The aim of this study was to analyze the prognostic value of systemic HMGB1 levels in HF patients with ischemic and non-ischemic cardiomyopathy. |
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