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三阴性乳腺癌与非三阴性乳腺癌的超声特征探讨
引用本文:刘畅,王学梅,李银燕,耿晶,张义侠. 三阴性乳腺癌与非三阴性乳腺癌的超声特征探讨[J]. 中国医学影像技术, 2012, 28(9): 1677-1681
作者姓名:刘畅  王学梅  李银燕  耿晶  张义侠
作者单位:中国医科大学附属第一医院超声科,辽宁沈阳,110001
摘    要:目的探讨三阴性乳腺癌(TNBC)的超声图像特征。方法回顾性分析148例经病理证实的乳腺癌患者,根据术后免疫组化结果,将其分为TNBC组(n=51)和非TNBC组(n=97),比较两组的声像图特征。结果 "边界不清"、"毛刺征"、"高回声晕"、"微小钙化"、"血流分级2~3级"、"腋窝淋巴结转移"在TNBC组分别占56.86%(29/51)、43.13%(22/51)、41.17%(21/51)、13.72%(7/51)、41.17%(21/51)、68.62%(35/51),在非TNBC组分别占87.62%(85/97)、81.44%(79/97)、76.28%(74/97)、56.70%(55/97)、79.38%(77/97)、48.45%(47/97),差异均有统计学意义(P均<0.05);而"后方回声衰减"、"纵横比>1"、"阻力指数≥0.7"在TNBC组分别占64.70%(33/51)、45.09%(23/51)、47.05%(24/51),在非TNBC组分别占56.70%(55/97)、30.92%(30/97)、61.85%(60/97),差异均无统计学意义(P均>0.05)。结论 TNBC的声像图表现具有一定特征性,有助于术前诊断。

关 键 词:乳腺肿瘤  超声检查
收稿时间:2012-03-28
修稿时间:2012-06-20

Ultrasonic features of the triple negative breast cancer andnon-triple negative breast cancer
LIU Chang,WANG Xue-mei,LI Yin-yan,GENG Jing and ZHANG Yi-xia. Ultrasonic features of the triple negative breast cancer andnon-triple negative breast cancer[J]. Chinese Journal of Medical Imaging Technology, 2012, 28(9): 1677-1681
Authors:LIU Chang  WANG Xue-mei  LI Yin-yan  GENG Jing  ZHANG Yi-xia
Affiliation:Department of Ultrasound Diagnosis, the First Affiliated Hospital of China Medical University, Shenyang 110001, China;Department of Ultrasound Diagnosis, the First Affiliated Hospital of China Medical University, Shenyang 110001, China;Department of Ultrasound Diagnosis, the First Affiliated Hospital of China Medical University, Shenyang 110001, China;Department of Ultrasound Diagnosis, the First Affiliated Hospital of China Medical University, Shenyang 110001, China;Department of Ultrasound Diagnosis, the First Affiliated Hospital of China Medical University, Shenyang 110001, China
Abstract:Objective To investigate the ultrasonic features of the triple negative breast cancer (TNBC). Methods According to immunohistn ochemical staining technique, 148 patients with histopathologically confirmed breast cancer were divided into TNBC group (n=51) and non-TNBC group (n=97). The malignant ultrasonic characteristics of TNBC were analyzed and compared with those of non-TNBC. Results The percentage of "irregular morphology", "burrs margin", "hyper halo echo", "cluster micro-calcification", "blood stream grade of 2 to 3" and "lymph nodes metastasis" was 56.86% (29/51), 43.13%(22/51), 41.17% (21/51), 13.72% (7/51), 41.17% (21/51) and 68.62% (35/51) respectively in TNBC group, while in non-TNBC group was 87.62% (85/97), 81.44% (79/97), 76.28% (74/97), 56.70% (55/97), 79.38% (77/97) and 48.45% (47/97), respectively (all P<0.05). The percentage of "posterior echo attenuation", "aspect ratio more than 1" and "resistance index more than or equal to 0.7" in TNBC group was 64.70% (33/51), 45.09% (23/51) and 47.05% (24/51), while in non-TNBC group was 56.70% (55/97), 30.92% (30/97) and 61.85% (60/97), respectively (all P>0.05). Conclusion Ultrasonic malignant features of TNBC have some characteristics, and contribute to prediagnosis of TNBC.
Keywords:Breast neoplasms  Ultrasonography
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