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| 梅花参的化学成分研究 | |
| 引用本文： | 鄢春红,丁萍月,陈莉莉,刘景凌,巫军. 梅花参的化学成分研究[J]. 中国海洋药物, 2007, 26(2): 27-29 |
| 作者姓名： | 鄢春红 丁萍月 陈莉莉 刘景凌 巫军 |
| 作者单位： | 1. 浙江省宁波市西门医院,浙江,宁波,315016 2. 宁波生物医药技术研究有限公司,浙江,宁波 3. 浙江大学宁波博士后流动站,浙江,宁波,315201 |
| 摘 要： | 目的研究梅花参体内的化学成分。方法利用DA101大孔树脂，硅胶，ODS Rp C-18反相硅胶，Sephadex LH-20柱色谱和HPLC方法进行分离纯化．根据所得化舍物的理化性质和波谱与质谱数据（尤其是2D-NMR和ESI—MS技术）．鉴定其结构。结果得到4个化合物．分别鉴定为：holothuriaA（1）,胸腺嘧啶（2），尿嘧啶（3），胆甾醇（4）。结论4个化舍物均为首次从该种动物中得到。 |
| 关 键 词： | 梅花参 胸腺嘧啶 尿嘧啶 胆甾醇 |
| 文章编号： | 1002-3461（2007）02-0027-03 |
| 修稿时间： | 2006-09-12 |
Study on the chemical constituents of sea cucumber Thelenota ananas(Jaeger) |
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| YAN Chun-hong,DING Ping-yue,CHEN Li-li,LIU Jing-ling,WU Jun. Study on the chemical constituents of sea cucumber Thelenota ananas(Jaeger)[J]. Chinese Journal of Marine Drugs, 2007, 26(2): 27-29 | |
| Authors: | YAN Chun-hong DING Ping-yue CHEN Li-li LIU Jing-ling WU Jun |
| Affiliation: | 1. Xi Men Hospital of Ningbo, Ningbo 315016, China ; 2. Ningbo Biomedical Research Institution, Ningbo 315201, China; 3. Ningbo Post-doctor Workstation of Zhejiang University, Ningbo 315201, China |
| Abstract: | Objective To study the chemical constituents of sea cucumber Thelenota ananas.Methods The compounds were isolated and purified from the sea cucumber Thelenota ananas by multi-chro- matography on Silica gel,ODS Rp C-18 gel,DA101 resin,Sephadex LH-20 and HPLC methods. Their structures were elucidated according to their spectral and MS data and also physicochemical properties character.Results Four compounds were isolated from the sea cucumber,and they were identified as:holothuria A(1),thymine(2),uracil(3),cholesterol(4).Conclusion Compounds 1-4 were obtained from this kind of sea cucumber for the first time. |
| Keywords: | holothuria A |
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