尼莫地平治疗急性脑外伤临床效果分析

目的 研究尼莫地平对急性脑外伤蛛网膜下腔出血脑血流速度的改变，以及颅内压增高支尼莫地平治疗作用的影响。

Clinical Effect of Nimodipine on Acute Head Injury

Objective To study the changes of cerebral blood flow (CBF) and the effeCtsof intracranial pressure (ICP) on nimodipine treating acute traumatic subarachnoid hemorrhage (t - SAH). Methods Seventy - five patients with traumatic subarachnoid hemorrhagehospitalized in our hOSPital from January 1996 to Apec 1997, were randomly divided into thetreatment group and the control group. Transcranial DoPPler (TCD) was ugh to deter CBFvelocity chance and ICP was observed. Results For the patients whose GCS > 9, in thecontrol group, among 18 cases, there were 13 caac whose CBF velocity increase; but in thetyffitmeflt group, amoflg 13 cases, only increase in 3 cases. In the treatmwt greup, among19 cases whose ICP>200 mmH2O, there were 15 cases whose CBF velocity increased; butamong 11 caac whose ICP < 200 mmH2O, only increase in 4 cases. Conclusion Nimodipinecan prevent CBF velocity from booming too fast in acute t-SAH and improve the treatingresults. And the increased ICP might affect the treatment of nimodipine.