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自固化磷酸钙人工骨修复四肢骨缺损的初步临床应用
引用本文:陈统一,王文波,李力,李晓东,傅云根,陈中伟. 自固化磷酸钙人工骨修复四肢骨缺损的初步临床应用[J]. 中华创伤杂志, 1999, 15(3): 184-186
作者姓名:陈统一  王文波  李力  李晓东  傅云根  陈中伟
作者单位:1. 200032,上海医科大学附属中山医院骨科
2. 内蒙古医学院第二附属医院骨科
3. 江西省宜春地区医院骨科
基金项目:国家自然科学基金,上海市启明星计划基金,上海市科委重点资助
摘    要:目的 研究自固化磷酸钙水泥(ACPC)人工骨修复非负重或低负重部位骨缺损的临床应用。方法 应用ACPC人工骨修复30例患者36处非负重或低负重部位骨缺损,平均年龄26.5岁。骨缺损大小均为15cm^2,骨缺损病因依次为骨折、骨囊肿、骨纤维结构不良、内生软骨瘤和髂骨供骨区等。观察患者术中ACPC固化时间,术后全身及切口局部反应,血钙、磷值变化,X线片和CT扫描。随访平均时间9.4个月。结果 全部患者

关 键 词:四肢骨缺损 骨折愈合 人工骨 修复 ACPC
修稿时间:1999-01-20

Clinical Application of Autosolidification Calcium Phosphate Cement to Repair Bone Defects: A Preliminary Report
CHEN Tongyi,WANG Wenbo,LI Li,et al.. Clinical Application of Autosolidification Calcium Phosphate Cement to Repair Bone Defects: A Preliminary Report[J]. Chinese Journal of Traumatology, 1999, 15(3): 184-186
Authors:CHEN Tongyi  WANG Wenbo  LI Li  et al.
Affiliation:CHEN Tongyi,WANG Wenbo,LI Li,et al. Dept. of Orthopaedics,Zhongshan Hospital,Shanghai Medical University,Shanghai,200032
Abstract:Objective Clinical applications of the autosolidification calcium phosphate cement (ACPC) to repair human bone defects were researched. Methods We implanted the ACPC artificial bone to repair 36 bone defects of 30 patients at non-or low-weight bearing site, with the average age of 265 years, the average size of defects was 15 cm2 The bone defects were resulted from fracture, bone cyst, fibrous dysplasia, enchondroma, etc. We observed the ACPC setting time intraoperatively, the systemic annd local reactions, the fluctuations of werum calcium and phosphate, and signs of x-ray and CT examinations postoperatively. The follow-up averaged 94 months. Results Neither allergic or toxic reaction nor fluctuation of serum calcium and phosphate were found in all patients. The radiological examination showed that the implanted ACPC was directly bonded to the bone at the interface and the bone contour at the defect sites was successfully restored. The ACPC setting time extended in 3 cases, incision redness and swelling in 2, oozing light yellow fluids in 4, and wound dehiscence in 1 All wounds healed through dressing changes. Conclusions ACPC, with good biocompatibility and plasticity, no toxicity, is suitable for repairing human bone defects at low-or non-weight bearing site.
Keywords:Fracture healingReoperationBone   artificialColoboma   boneAutosolidification calcium phosphate cement
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