Highly sensitive mutation assay for mutagenicity monitoring of indoor air using Salmonella typhimurium YG1041 and a microsuspension method |
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| Authors: | Azuma Shun-ichi; Kishino Satoru; Katayama Seiji; Akahori Yukio; Matsushita Hidetsuru |
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| Institution: | 1Laboratory of Physical Chemistry, School of Pharmaceutical Sciences 52-1 Yada, Shizuoka 422, Japan
2Division of Environmental Health Sciences, Graduate School of Nutritional and Environmental Sciences, University of Shizuoka 52-1 Yada, Shizuoka 422, Japan |
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| Abstract: | A highly sensitive mutation assay for indoor mutagenicity monitoringwas investigated by a combination of Salmonella typhimuriumYG strains and the microsuspension method. Tester strains wereYG1024, YG1029, YG1041 and YG1042. YG1041 gave the highest sensitivityin the mutagenicity test for the extracts of airborne particulates.The sensitivity of the microsuspension assay using S.typhimuriumYG1041 in the absence of S9 mix was |
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