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Is Colombia reaching the goals on infant immunization coverage? A quantitative survey from 80 municipalities
Institution:1. AHEPA University Hospital, Thessaloniki, Greece;2. Hospital Clinic of University of Barcelona, Barcelona, Spain;3. CardioVascular Center Frankfurt, Frankfurt, Germany;4. University Hospital of Bern, Bern, Switzerland;5. University Hospital of Bonn, Bonn, Germany;6. Fondazione Toscana Gabriele Monasterio, Massa, Italy;7. Ospedale Careggi di Firenze, Florence, Italy;8. St-Luc University Hospital, Brussels, Belgium;9. Centre Hospitalier Universitaire de Charleroi, Charleroi, Belgium;10. University Hospital of Zurich, Zurich, Switzerland;11. Aarhus University Hospital, Skejby, Denmark;12. University Hospital of Salamanca, Salamanca, Spain;13. Imperial College Healthcare NHS Trust, London, United Kingdom;14. Montreal Heart Institute, Montreal, Canada;15. Universitätsmedizin Göttingen, Göttingen, Germany;p. Coburg Hospital, Coburg, Germany;1. Pharmaceutical physical chemistry laboratory, Department of Pharmacy, Faculty of Natural Sciences, ICESI University, Cali, Colombia;2. SIT Biotech GmbH, BMZ 2 Otto-Hahn-Str. 15, 44227 Dortmund, Germany
Abstract:ObjectivesThis study aimed to evaluate the coverage of the Colombian Expanded Program on Immunization among children less than 6 years old, to evaluate the timeliness of immunization, to assess the coverage of newly introduced vaccines, and to identify factors associated with lack of immunization.MethodsWe conducted a cross-sectional survey in 80 municipalities of Colombia, using a two-stage cluster random sampling. We attempted to contact all children less than 6 years old living in the sampled blocks, and asked their caregivers to provide immunization record cards. We also collected basic sociodemographic information.ResultsWe reached 81% of the attempted household contacts, identifying 18,232 children; of them, 14,805 (83%) had an immunization record card. Coverage for traditional vaccines was above 90%: BCG (tuberculosis) 95.7% (95%CI: 95.1–96.4), pentavalent vaccine 93.3% (92.4–94.3), MMR (measles, mumps, rubella) initial dose 94.5% (93.5–95.6); but it was lower for recently introduced vaccines: rotavirus 80% (77.8–82.1), influenza 48.4% (45.9–50.8). Results for timely vaccination were not equally successful: pentavalent vaccine 44.2% (41.4–47.1), MMR initial dose 71.2% (68.9–73.4). Mother’s education was significantly associated with higher immunization odds. Older age, a greater number of siblings, low socioeconomic status, and not having health insurance were significantly associated with lower immunization odds. There was significant heterogeneity in immunization rates by municipality across the country.ConclusionsAlthough absolute immunization coverage for traditional vaccines met the goal of 90% for the 80 municipalities combined, disparities in coverage across municipalities, delayed immunization, and decline of coverage with age, are common problems in Colombia that may result in reduced protection. Newly introduced vaccines require additional efforts to reach the goal. These results highlight the association of health inequities with low immunization coverage and delayed immunization. Identification of vulnerable populations and their missed opportunities for vaccination may help to improve the reach of immunization programs.
Keywords:Colombia  Vaccination  Immunization schedule  Immunization programs  Risk factors  Immunization coverage  Timely immunization  Underutilized vaccines
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