Positron emission tomography for predicting malignancy of sinonasal inverted papilloma |
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| Authors: | Shojaku Hideo Fujisaka Michiro Yasumura Satsuki Ishida Masayuki Tsubota Masahito Nishida Hiroshi Watanabe Yukio Kawano Masaya Shimizu Masashi Fukuoka Jyunya |
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| Affiliation: | Department of Otolaryngology, University of Toyama, Toyama, Japan. hshojaku@med.u-toyama.ac.jp |
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| Abstract: | BACKGROUND: Sinonasal inverted papilloma (IP) is an uncommon nasal tumor. It is known for being locally invasive and recurrent, with a high probability of malignant transformation. Accurate initial staging and close surveillance are critical in the management of the disease. METHODS AND RESULTS: Fluorine-18 fluorodeoxyglucose positron emission tomography (FDG PET) was performed in 5 patients with IP. High FDG uptake (maximum standardized uptake (SUVmax) value >3.0) was observed in all patients, and 2 patients with IP associated with squamous cell carcinoma (SCC) exhibited higher SUVmax values. CONCLUSION: The SUVmax value of a sinonasal tumor can warn the surgeon of the probability of an associated malignancy, even when preoperative biopsy demonstrates a purely benign papilloma. |
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