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Prenatal origin of childhood AML occurs less frequently than in childhood ALL |
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| Authors: | Tatiana Burjanivova Jozef Madzo Katerina Muzikova Claus Meyer Bjoern Schneider Felix Votava Rolf Marschalek Jan Stary Jan Trka Jan Zuna |
| Affiliation: | (1) CLIP – Childhood Leukaemia Investigation Prague, Czech Republic;(2) Department of Pediatric Hematology and Oncology, Charles University Prague, 2nd Medical School, Czech Republic;(3) Institute of Pharmaceutical Biology/DCAL, University of Frankfurt, Frankfurt/Main, Germany;(4) Department of Pediatrics, Charles University Prague, 3rd Medical School, Czech Republic |
| Abstract: | BackgroundWhile there is enough convincing evidence in childhood acute lymphoblastic leukemia (ALL), the data on the pre-natal origin in childhood acute myeloid leukemia (AML) are less comprehensive. Our study aimed to screen Guthrie cards (neonatal blood spots) of non-infant childhood AML and ALL patients for the presence of their respective leukemic markers. |
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