临床药师干预促进骨科合理预防使用抗菌药物的效果评价

目的:评价临床药师参与骨科清洁切口手术围手术期预防应用抗菌药物管理的效果.方法 :抽取2015年12月(干预前)和2016年4月(干预后)出院的骨科清洁切口手术的所有病例,将临床药师干预前后预防应用抗菌药物的各项指标进行对比.结果 :临床药师参与管理后(干预后),骨科清洁切口手术围手术期预防应用抗菌药物在药物品种选择和给药时机方面有所改变(P<0.01),用药疗程较干预前明显缩短(P<0.01);干预后病人人均抗菌药物费用较干预前明显降低(P<0.01).结论 :临床药师对骨科清洁切口手术围术期预防应用抗菌药物的干预,提高了抗菌药物使用的合理性,对降低病人抗菌药物费用,规范医院合理用药有一定意义.

Effect of clinical pharmacist intervention on promoting the rational use of antibiotics in orthopaedics

Objective:To evaluate the effects of pharmacist intervention on preventive use antibiotics in perioperation of clean incision. Methods:All patients with clean incision operation in December 2015 ( pre-intervention group ) and April 2016 ( post-intervention group ) were selected. The indicators of preventive use of antibiotics between before and after intervention of clinical pharmacist were compared. Results:After clinical pharmacist intervention, the administration time and drug variety of preventive use antibiotics in perioperation of clean incision changed(P<0. 01),the course of drug use was significantly shortened(P<0. 01),and the drug expense significantly decreased compared before intervention(P<0. 01). Conclusions:The pharmacist intervention on preventive use antibiotics in perioperation of clean incision has a certain significance in promoting the rational use of antibacterial drug and decreasing the expense of antibacterial drug.