妊娠期肝内胆汁瘀积症对新生儿生存质量的影响

目的 :探讨孕妇肝内胆汁瘀积症(ICP)对胎儿的影响。方法 :应用放免法对确认为ICP的60例患者在分娩时分别测定母血与新生儿脐静脉血清肝胆酸(CG)水平。结果 :60例ICP母亲所生新生儿的窒息率为28.3% ,显著高于同期40例正常孕妇的新生儿窒息率7.5 %。结论 :ICP致胎儿血清CG升高是引起胎儿窒息的重要原因之一。

Influence of newborn exist molar on intrahepatic chotestasic of pregnancy

Objective:To explore the of intropepatic chotestasis of mother to fetus during pregnance.Methods:Serum chotegtycine(CG)in 60 gravidas with ICP and funiculus vein blood at detivery and in their babies on second day after born were measured using radiodmmunoassay,respectively .Results:The results showed that the serum CG value in 74.3% of babies and 83.3% of funiculus vein blood samples were higher than in their mothe,the incidance rate of newborn asphyaxiation in 60 mother with ICP was higher than in 40 narmal mother (28.3%vs 7.5% infuence ). Conclusion:This srudy indicates that the high serum CG state in fatuscaused from ICP of mother was a important factor of mother was a important factor of newborn asphyasxiation.