不育患者精浆酸性磷酸酶和前列腺特异抗原含量与精子质量的关系

目的探讨不育患者精浆酸性磷酸酶（ACP）和前列腺特异抗原（PSA）含量与精子质量的关系。方法随机选择男性不育症患者122例，采用精子分析仪测定精液参数，同时用酶联免疫吸附试验（ELISA）法检测精浆中PSA水平，用磷酸苯二钠法检测精浆中ACP含量，并分析其与精子密度、活力和黏度的关系。结果精子活力异常组精浆ACP、PSA含量明显低于活力正常组，两组比较差异有统计学意义（P〈0．05）；精液黏度增高组精浆ACP、PSA含量明显低于精液黏度正常组，两组比较差异有统计学意义（P〈0．05）。精子密度正常组ACP高于密度减低组（P〈0．05），PSA含量两组无明显差异。结论精浆ACP、PSA含量与精子质量有密切关系。

Relationship between seminal acid phosphatase,prostate specific antigen and sperm quality in male infertility patients

Objective To investigate the relationship between seminal acid phosphatase（ACP） ,prostate specific antigen（PSA） and the quality of sperm. Methods 122 infertile patients were collected randomly. The semens were analyzed by the GASA, the level of PSA in seminalplasma was detected by ELISA method and ACP activity was examined by di-sodium phenyl phosphate. Results ACP and PSA of obnormal sperm motility group were significanlty lower than those of normal sperm motility group（P〈0.05）. The semen hyperviscosity group were significanlty lower than normal viscosity group in ACP and PSA（P〈0. 05）. ACP in normal sperm density group was higher than that of reduced sperm density group （P〈0.05）. PSA had no significant difference between the two groups. Conclusion The seminal acid phosphatase and prostate specific antigen are correlated with the sperm quality.