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Proliferating Brenner tumor: case report
Authors:Kourda N  Elloumi H  Chérif K  Ben Jilani S  Zermani R
Affiliation:1. Service de gynécologie obstétrique et médecine de la reproduction, FEH, CHU de Caen, avenue de la Côte-de-Nacre, 14033 Caen cedex, France;2. Service de gynécologie obstétrique, centre hospitalier de l’Ouest Guyanais, 16, boulevard du Général-Leclerc, BP 245, 97393 Saint-Laurent du Maroni, Guyane française;3. Université de médecine de Caen Basse-Normandie, CHU de Caen, avenue de la Côte-de-Nacre, 14033 Caen cedex, France;4. Service de santé publique, centre hospitalier de l’Ouest Guyanais, 16, boulevard du Général-Leclerc, BP 245, 97393 Saint-Laurent du Maroni, Guyane française;1. Department of Obstetrics and Gynaecology, Universitary Hospital Estaing, Clermont-Ferrand, France;2. Centre Jean Perrin, Surgical Oncology Department, Clermont-Ferrand, France;1. Service de gynécologie-obstétrique, maternité régionale universitaire de Nancy, 10, rue du Dr-Heydenreich, 54042 Nancy cedex, France;2. Faculté de médecine de Nancy, université de Lorraine, 54500 Vandœuvre-lès-Nancy, France;1. Institut Bergonié, département d’oncologie médicale, 229, cours de l’Argonne, 33076 Bordeaux, France;2. Institut Gustave-Roussy, service d’anatomopathologie, 114, rue Édouard-Vaillant, 94805 Villejuif, France;3. Institut Bergonié, département d’imagerie médicale, 229, cours de l’Argonne, 33076 Bordeaux, France;4. Institut Gustave-Roussy, université Paris-Sud, service de médecine nucléaire et de cancérologie endocrinienne, 114, rue Édouard-Vaillant, 94805 Villejuif, France;5. Institut Bergonié, département de médecine nucléaire et de cancérologie thyroidienne, 229, cours de l’Argonne, 33076 Bordeaux, France;1. Peritoneal Surface Malignancies Unit, Istituto Nazionale dei Tumori, Milan, Italy;2. Department of Surgery A, Tel- Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel;3. Department of Surgical Oncology, Centre Hospitalier Lyon Sud, Pierre-Benite, France;4. Charles Nicolle University Hospital, Rouen, France;5. L''Archet II, University Hospital, Nice, France;6. Gustave Roussy Institute, Villejuif, France;1. Department of Obstetrics and Gynecology, University of Insubria, Varese, Italy;2. Department of Gynecologic Oncology, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Italy
Abstract:Brenner tumors account for only 1 to 2% of ovarian tumors. Proliferating Brenner tumors are characterized by an epithelial proliferation, resembling superficial well-differentiated urothelial carcinomas. A single 29-year-old patient was operated for an ovarian tumor. On gross examination, the tumor, which originated in the left ovary, was cystic multilocular and presented polyoid excrescences. Definitive histological exam showed a papillary proliferation lined by transitional cells without stroma infiltration. Mucinous cells lined some cavities. The diagnosis of proliferating Brenner tumor was made. Clinical and pathological characteristics of this rare entity will be discussed.
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