早期先兆流产合并支原体感染的抗生素治疗

目的：探讨在孕12周（停经84天）前的早期先兆流产合并支原体感染的住院患者的治疗中使用抗生素对治疗是否有效。方法：回顾分析2008-01-2012-12间孕12周（停经84天）前的早期先兆流产共507名患者的临床资料，有204名患者行宫颈分泌物培养，共63名住院患者有支原体感染。将其分为治疗组（42例）和对照组（21例），比较两组的疗效。结果：治疗组总有效率（97．62％）高于没有使用抗生素的对照组（90．48％）（疗效比较P〈0．05，差异有统计学意义）。结论：宫颈分泌物培养有支原体感染的早期先兆流产患者根据药敏结果使用抗生素治疗明显提高保胎患者的疗效，建议早期先兆流产合并支原体感染的患者应根据药敏试验结果，用最小有效剂量，以最短必需疗程，使用最敏感药物。

ANTIBIOTIC THERAPY OF EARLY THREATENED ABORTION AND MYCOPLASMA IN FECTION

Objective：To investigate the effect of antibiotic therapy on hospitalized patients with early threatened abortion （ before 12 gestational weeks） and mycoplasma infection. Methods： Clinical data of 507 patients with early threatened abortion between Jan. 2008 and Dec. 2012 were retrospectively analyzed. Cervical wecretion from 204 patients was collected and examined. Mycoplasma infection was found in 63 patients. These patients were divided into treatment group （ n = 42） and control group （ n = 21 ）. Efficacy of that anti- biotic therapy was compared between the two groups. Results： Total effective rate was higher in treatment group （97.62%） than in control group （90.48%） （P 〈 O. 05）. Conclusion： According to results of drug sensitivity, appropriated antibiotics can be chosen to effectively increase curative effect in fetus protection. It is suggested that minimum dose of most sensitive drugs should be used to treat the patients with early threatened abortion and mycoplasma infection to shorten indispensable course of treatment.