鼠神经生长因子对急性脑梗死患者神经功能康复的临床疗效观察

目的：观察鼠神经生长因子治疗急性脑梗死的治疗效果。方法：将120例急性脑梗死患者随机分为治疗组与对照组，各60例，对照组只进行脑梗死的常规基础治疗，治疗组在常规基础治疗的基础上加用鼠神经生长因子（NGF）（北大之路，恩经复18ug≥9000AU），18ug，im，qd，分别于治疗前及治疗后第3周和第6周对所有患者进行神经功能缺损程度进行美国国立卫生院脑卒中量表（NIHSS）评分并比较。结果：治疗前两组脑卒中患者神经功能缺损NIHSS评分无统计学意义（P〉0．05），治疗后第6周两组脑卒中患者神经功能缺损NIHSS评分显示治疗组显著低于对照组（P〈0．05）。结论：鼠神经生长因子（NGF）能较快速的促进患者的神经功能恢复，对急性脑梗死治疗有很大临床意义，是一种有效的治疗急性脑梗死的药物。

TO OBSERVE THE CLINICAL EFFICACY OF MOUSE NERVE GROWTH FACTOR ON ACUTE CEREBRAL INFARCTION

Objective ： To observe the effect of Mouse nerve growth factor in the treatment of acute cerebral infarction. Methods： 120 patients with acute cerebral infarction were randomly divided into treatment group and control group, each of which had 60 cases. The control group only received the conventional treatment of cerebral infarction, the treatment group based on conventional therapy plus Mouse nerve growth factor （NGF）, 1Bug, im, QD, American National Institutes of Health Stroke Scale before treatment and after third,sixth weeks treatment was performed on all patients with neurological deficit （NIHSS） score and comparisien. Results： Before treatment, two groups of cerebral apoplexy nerve function defect scores of NIHSS had no statistical significance （ P 〉 0.05 ）, sixth weeks and two set of neural function of stroke patients with NIHSS showed that the effect of the treatment group was significantly lower than that of the control group （P 〈 0. 05）. Conclusion：Mouse nerve growth factor （NGF） can help patients with rapid neural function recovery and has great clinical significance for the treatment of acute cerebral infarction, whinh is an effective drug for the treatment of acute cerebral infarction.