| 支气管哮喘病人外周血单核/巨噬细胞IL-15的分泌水平 |
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| 引用本文： | 吕冬梅,黄瑾,吕春平.支气管哮喘病人外周血单核/巨噬细胞IL-15的分泌水平[J].中国病理生理杂志,1999,15(7):626-627. |
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| 作者姓名： | 吕冬梅 黄瑾 吕春平 |
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| 作者单位： | 1. 白求恩医科大学附属第二临床医学院,长春,130041
2. 白求恩医科大学预防医学院,长春,130041 |
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| 摘 要： | 目的和方法：利用改良的ＭＴＴ比色法测定ＣＴＬ１２细胞增殖程度而确定Ｉ国５水平的方法，测定了２７例支气管哮喘急性发作期病人和４０例健康人外周因单核／巨噬细胞培养上清中ＩＬ－１５的分泌水平。结果：无论刺激与否，哮喘病人ＩＬ－１５水平均高于健康对照组，两组差异显著。结论：哮喘病人外周血单核／巨噬细胞ＩＬ－１５的分泌水平异常可能参与了哮喘的发病。
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| 关 键 词： | 白细胞介素15 单核细胞 巨噬细胞 哮喘 |
Levels of IL-15 in supernatant of monocytes/macrophages in patients with bronchial asthma |
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| LU Dong-Mei,HUANG Jin,LU Chun-Ping.Levels of IL-15 in supernatant of monocytes/macrophages in patients with bronchial asthma[J].Chinese Journal of Pathophysiology,1999,15(7):626-627. |
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| Authors: | LU Dong-Mei HUANG Jin LU Chun-Ping |
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| Abstract: | AIM and METHODS:
Interleukin (IL-15) is a newly described cytokine with an action similar to that of IL-2. In this
study, the levels of IL-15 in the supernatants of LPS-stimulated (or not)
monocytes/macrophages were examined in 27 patients with bronchial ashma at acute phase,
and were compared with healthy controls. RESULTS:Signifcant elevation of IL-15 was observed
in supernatants of monocytes/macrophages from patients with asthma as compared with that in
normal individuals, whether LPS existed or not.CONCLUSION:IL-15 plays a role in asthma. |
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| Keywords: | Interleukin-15 Monocytes Macrophages Asthma |
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