Analysis of the Immune Responses of Mice to Infection with Leishmania braziliensis |
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| Authors: | Gregory K. DeKrey Hermenio C. Lima Richard G. Titus |
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| Affiliation: | Department of Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523-1671 |
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| Abstract: | Leishmania major and Leishmania braziliensis both cause cutaneous leishmaniasis, but the former kills BALB/c mice while the latter is killed by the mice. This killing of L. braziliensis occurred by a gamma interferon-dependent mechanism, potentially made possible by the observed lack of high interleukin-4 production. |
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